Neutrophil elastase inhibitor prevents ischemic brain damage via reduction of vasogenic edema
نویسندگان
چکیده
منابع مشابه
Vasogenic Brain Edema Formation
Brain edema (BE) research lacks quantitative regional methods. We modified the method of Pappius and McCann (1969), who used radioactive iodinated P serum albumin (R1SA) as a label for vasogenic BE fluid. To correct for intravascular plasma volume we used Cr^ labelled red blood cells and calculated equivalent extravascular plasma volume (EVPV). The modified RISA method was compared with a stand...
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We read with interest the article by Almasi et al. on a 48 years old female patient with Mitochondrial Encephalomyopathy, Lactic Acidosis, And Stroke-like episodes (MELAS), diagnosed based on the clinical presentation, blood test results, and imaging and muscle biopsy findings . We have the following comments and concerns.
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Grades of recovery and outcome of patients with "stroke" have been widely reported by different authors.' There is reasonable agreement on the "poor" outcome of a certain number of surviving "stroke" patients; their number is widely estimated to vary from 19% to 35%. With the growing need for physical medicine and rehabilitation treatment and the associated mushrooming financial expenditures fo...
متن کاملIschemic Brain Edema and Compression Brain Edema
Grades of recovery and outcome of patients with "stroke" have been widely reported by different authors.' There is reasonable agreement on the "poor" outcome of a certain number of surviving "stroke" patients; their number is widely estimated to vary from 19% to 35%. With the growing need for physical medicine and rehabilitation treatment and the associated mushrooming financial expenditures fo...
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background sivelestat is a neutrophil elastase inhibitor (nei) with positive impact on the respiratory complications in thoracic surgery. based on the findings of a recent study, nei may have a good response for avoiding ischemia reperfusion injury in liver resection. conclusions intravenous nei administration had positive impact on the postoperative inflammatory response and oxygenation while ...
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ژورنال
عنوان ژورنال: Hypertension Research
سال: 2010
ISSN: 0916-9636,1348-4214
DOI: 10.1038/hr.2010.58